Case Study: Supplier Qualification and Audit Program for a Fill & Finish Manufacturer

Case Study Overview

Supplier qualification and audit program in sterile manufacturing are essential to ensure compliance, protect supply continuity, and meet rising regulatory expectations. Without a structured framework, supplier-related issues can cause production delays, increase deviations, and trigger negative audit outcomes. This case study highlights how GMP Bridge helped a mid-sized sterile fill & finish manufacturer in Spain establish a robust supplier qualification and audit program — delivering improved oversight, reduced risks, and long-term sustainability.

The Challenge

A mid-sized sterile fill & finish manufacturer in Spain relied on an expanding supplier network but lacked a structured program for supplier qualification and oversight. This created inconsistent evaluations, delayed approvals, production disruptions, and increasing pressure from clients and regulators to improve supplier management.

Quick Summary

Region: Spain
Company Type: Mid-sized sterile fill & finish manufacturer
Products: Sterile liquid drug products

Solution Delivered

Mapped all GMP-relevant suppliers and service providers, including CMOs and testing labs
Applied risk-based prioritization criteria to focus on critical suppliers.
Designed a standardized supplier qualification process with clear approval workflows.
Developed an annual audit plan targeting high-risk and strategic suppliers.
Executed remote and on-site supplier audits led by GMP Bridge auditors.
Trained internal QA teams in supplier management and audit readiness.

Impact and Results

Improved control and visibility across the entire supplier network.
Implemented a risk-based qualification and monitoring strategy.
Expanded audit coverage of critical suppliers and outsourced processes.
Reduced supplier-related production delays and compliance risks.
Empowered QA teams to sustain and own the program autonomously.

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