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Case Study 7. Supplier Qualification and Audit Program

Supplier Qualification and Audit Program for Fill & Finish Manufacturer

   

Client Profile


  • Country: Austria
     
  • Type of Company: Mid-sized sterile fill & finish manufacturer
     
  • Products: Sterile liquid drug products
     

Challenge


The client relied on a growing network of raw material and service providers but lacked a structured approach to supplier qualification and oversight. This led to:


  • Inconsistent supplier evaluations and qualification processes
     
  • Limited visibility of supplier risks and compliance gaps
     
  • Delayed approvals and disruptions in production due to missing documentation
     
  • Weak audit coverage of key material suppliers and service providers
     
  • Increasing pressure from clients and authorities to improve supplier management
     

Solution Delivered


GMP Bridge supported the client with the design and rollout of a risk-based Supplier Qualification and Audit Program:


  • Mapping of all GMP-relevant suppliers and service providers, including CMOs and testing labs
     
  • Prioritization using risk-based criteria to focus resources on critical suppliers
     
  • Development of a standardized supplier qualification process, including approval workflows and documentation requirements
     
  • Design of an annual audit plan focusing on high-risk and strategic suppliers
     
  • Execution of remote and on-site supplier audits by internal and GMP Bridge lead auditors
     
  • Development of a supplier monitoring dashboard with clear KPIs and follow-up actions
     
  • Training of internal teams in supplier management and audit readiness
     

Impact & Results


  • Improved control and visibility over the supplier network
     
  • Risk-based qualification and monitoring approach implemented
     
  • Increased audit coverage for critical suppliers and outsourced processes
     
  • Reduced supplier-related production delays and compliance risks
     
  • Strengthened position in client audits and regulatory inspections
     
  • Internal QA team trained to sustain and manage the program autonomously
     

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